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DC Field | Value | Language |
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dc.contributor.author | Osuolale, Olayinka O. | - |
dc.contributor.author | Danko, David | - |
dc.contributor.author | Bezdan, Daniela | - |
dc.contributor.author | et al | - |
dc.date.accessioned | 2022-05-20T12:25:10Z | - |
dc.date.available | 2022-05-20T12:25:10Z | - |
dc.date.issued | 2021-05-26 | - |
dc.identifier.citation | Danko, D., Bezdan, D., Afshin, E. E., Ahsanuddin, S., Bhattacharya, C., Butler, D. J., … Jackson, K. (2021). A global metagenomic map of urban microbiomes and antimicrobial resistance. Cell, 184(13), 3376–3393.e17. doi:10.1016/j.cell.2021.05.002 | en_US |
dc.identifier.uri | https://doi.org/10.1016/j.cell.2021.05.002 | - |
dc.identifier.uri | http://repository.elizadeuniversity.edu.ng/jspui/handle/20.500.12398/1353 | - |
dc.description | Staff Publication | en_US |
dc.description.abstract | We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60 cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial ecosystem. This atlas provides an annotated, geospatial profile of microbial strains, functional characteristics, antimicrobial resistance (AMR) markers, and genetic elements, including 10,928 viruses, 1,302 bacteria, 2 archaea, and 838,532 CRISPR arrays not found in reference databases. We identified 4,246 known species of urban microorganisms and a consistent set of 31 species found in 97% of samples that were distinct from human commensal organisms. Profiles of AMR genes varied widely in type and density across cities. Cities showed distinct microbial taxonomic signatures that were driven by climate and geographic differences. These results constitute a highresolution global metagenomic atlas that enables discovery of organisms and genes, highlights potential public health and forensic applications, and provides a culture-independent view of AMR burden in cities. | en_US |
dc.description.sponsorship | We thank these organizations, people, and grants for their support: the Tri-I Program in Computational Biology and Medicine (CBM) funded by NIH grant 1T32GM083937 ; etc | en_US |
dc.language.iso | en | en_US |
dc.publisher | Cell Journal by Elsevier | en_US |
dc.subject | metagenomic | en_US |
dc.subject | microbiomes | en_US |
dc.subject | antimicrobial resistance | en_US |
dc.title | A global metagenomic map of urban microbiomes and antimicrobial resistance | en_US |
dc.type | Article | en_US |
Appears in Collections: | Research Articles |
Files in This Item:
File | Description | Size | Format | |
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1-s2.0-S0092867421005857-main.pdf | 10.08 MB | Adobe PDF | View/Open |
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