Adewale, S. O.Omoloye, M. A.Olopade, I. A.Adeniran, G. A.2021-04-082021-04-082017-072351-8014http://repository.elizadeuniversity.edu.ng/handle/20.500.12398/954Staff PublicationA system of differential equation approach was used to model the dynamical spread of malaria where humans and vectors interact and infect each other. Positivity of solution showed that there exists a domain where the model is epidemiologically and mathematically well-posed. The basic reproduction number R0 < 1 shows that disease can be controlled in the environment, otherwise the disease persist and become endemic whenever R0 > 1. Also, the numerical analysis performed shows that the most effective strategies for controlling malaria is to reduce the vector biting rate and increased the human treatment.enMalaria,Humans,vectors,mathematical model,stability analysis,simulation study.Article