Detection of Urinary Tract Pathology in Some Schistosoma haematobium Infected Nigerian Adults

Abstract

Screening for Schistosoma haematobium infection and its possible morbidity was carried out in 257 adult participants in Eggua community,Ogun State,Nigeria. Parasitological assessment for the presence of ova of S. haematobiumin urine and abdominopelvic ultrasonographic examination for bladder and secondary kidney pathology were carried out. S. haematobiumprevalence of 25.68% (66/257) was recorded among the participants. There was a significantly higher prevalence of 69.2% of urinary schistosomiasis in the females than the prevalence of 31.8% inmales (𝑃 = 0.902). The intensity of infections was mostly light (55) (21.8%) compared to heavy (10) (3.9%) with themean intensity of 16.7 eggs/10mL urine. Structural bladder pathology prevalence among participants was 33.9%. The bladder and kidney pathologies observed by ultrasound in subjects with S. haematobium infections included abnormal bladder wall thickness (59%), abnormal bladder shape (15.2%), bladder wall irregularities (15.2%), bladder masses (1.5%), bladder calcification (1.5%), and hydronephrosis (3%). Infection with S. haematobium was associated with bladder pathology. Higher frequencies of bladder abnormalities were observed more in the participants with light intensity of S. haematobium infection than in those with heavy infection. More bladder pathology was also seen in women than in men, although this was not statistically significant. In conclusion, there is evidence that the development of bladder pathology may be associated with S. haematobium infection.