Please use this identifier to cite or link to this item:
Title: Relieving the tension in hypertension: Food–drug interactions and anti-hypertensive mechanisms of food bioactive compounds
Authors: Ajeigbe, Olufunke F.
Ademosun, Ayokunle Olubode
Oboh, Ganiyu
Keywords: angiotensin-I converting enzyme
Issue Date: 14-Jun-2020
Publisher: Wiley : Journal of Food Biochemistry
Citation: Ajeigbe, O. F., Ademosun, A. O., & Oboh, G. (2020). Relieving the tension in hypertension: Food–drug interactions and anti‐hypertensive mechanisms of food bioactive compounds. Journal of Food Biochemistry. doi:10.1111/jfbc.13317
Abstract: Hypertension is a global health problem. Statistics report from the World Health Organization reveals its prevalence in about a quarter of the world global population. Due to the complications associated with hypertension, it is required to be well managed or prevented pharmacologically or non-pharmacologically. Pharmacologically, the major antihypertensive drugs used are centrally acting sympatholytic drugs, diuretics, vasodilators, angiotensin converting enzyme inhibitors, and angiotensin II receptor blockers while non-pharmacological means of management include lifestyle changes, intake of diet or supplements with antihypertensive effects. Interestingly, the use of diet as a complement with drug intake has become very popular due to occurring side effects over time. Recent research efforts have revealed that foods such as fruits and vegetables contain bioactive substances that modulate the activities of macromolecules involved in the development, complications, and management of hypertension. Practical applications Recent research efforts have suggested the efficacy of diets rich in fruits and vegetables in the management of hypertension. This review examines some of the mechanisms involved in the dietary management or prevention of hypertension by bioactive compounds found in foods. This review promotes the use of diet in the management of the condition and also suggests that precautions to be taken in the combined use of food and drugs.
Description: Staff Publication
Appears in Collections:Research Articles

Files in This Item:
File Description SizeFormat 
Pages from 10.1111@jfbc.13317.pdf192.69 kBAdobe PDFThumbnail

Items in EUSpace are protected by copyright, with all rights reserved, unless otherwise indicated.