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Title: | Evaluation of antioxidant and hypolipidaemic effects of fermented Parkia biglobosa (Jacq) seeds in tyloxapol-induced hyperlipidaemic rats |
Authors: | Ayo-Lawal, Rachael A. Osoniyi, Omolaja Famurewa, Akindele J. Lawal, Olukayode A. |
Keywords: | Pakia biglobosa Hyperlipidaemia Total Cholesterol High density |
Issue Date: | 23-Sep-2012 |
Publisher: | IEEE |
Citation: | Ayo-Lawal, R. A., Osoniyi, O., Famurewa, A. J., & Lawal, O. A. (2014). Evaluation of antioxidant and hypolipidaemic effects of fermented Parkia biglobosa (Jacq) seeds in tyloxapol-induced hyperlipidaemic rats. Afr J Food Sci, 8(5), 225-232. |
Abstract: | Globally, fermented foods form an intricate part of the staple diet of people. This study investigated the hypolipidaemic potential of fermented seeds of Parkia biglobosa (African locust bean/iru), a popular condiment by supplementing (20% w/w) in animal feed. Animals (n= 5) in six treatment groups received; standard rat diet (control); iru-supplemented feed; standard rat feed with tyloxapol administered at the end of the experimental period (tyloxapol control); iru supplemented feed and triton at the end of the experimental period; standard feed with administration of fluvastatin sodium (40 and 80 mg/kg body weight) accordingly. Hyperlipidaemia was induced and ascertained by single intraperitoneal injection of 250 mg/kg triton WR 1339 (tyloxapol) constituted in normal saline. It was administered after six weeks experimental period to respective groups. The results revealed that addition of the fermented condiment into … |
URI: | http://repository.elizadeuniversity.edu.ng/jspui/handle/20.500.12398/641 |
ISSN: | 1996-0794 |
Appears in Collections: | Research Articles |
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Evaluation of antioxidant and hypolipidaemic effects of fermented Parkia biglobosa_seeds in tyloxapol_induced hyperlipidaemic rats.pdf | Article full-text | 390.85 kB | Adobe PDF | View/Open |
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