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Title: | Drying methods alter angiotensin-I converting enzyme inhibitory activity, antioxidant properties, and phenolic constituents of African Mistletoe (Loranthus bengwensis L) Leaves |
Authors: | Oboh, Ganiyu Omojokun, Olasunkanmi S. Ademiluyi, Adedayo O. |
Keywords: | Mistletoe Almond Drying Antioxidant Angiotensin-I converting enzyme (ACE) |
Issue Date: | Oct-2016 |
Publisher: | SAGE Publications |
Citation: | Oboh, G., Omojokun, O. S., & Ademiluyi, A. O. (2016). Drying methods alter angiotensin-I converting enzyme inhibitory activity, antioxidant properties, and phenolic constituents of African Mistletoe (Loranthus bengwensis L) Leaves. Journal of evidence-based complementary & alternative medicine, 21(4), 260-270. |
Abstract: | This study investigated the most appropriate drying method (sun drying, oven drying, or air drying) for mistletoe leaves obtained from almond tree. The phenolic constituents were characterized using high-performance liquid chromatography–diode array detector, while the inhibitory effect of the aqueous extracts of the leaves on angiotensin-I converting enzyme (ACE) was determined in vitro as also the antioxidant properties. Oven-dried extract (kidney [276.09 μg/mL] and lungs [303.41 μg/mL]) had the highest inhibitory effect on ACE, while air-dried mistletoe extract (kidney [304.47 μg/mL] and lungs [438.72 μg/mL]) had the least. Furthermore, the extracts dose-dependently inhibited Fe2+ and sodium nitroprusside-induced lipid peroxidation in rat’s heart and kidney. Also, all extracts exhibited antioxidative properties as typified by their radical scavenging and Fe-chelating ability. Findings from this study revealed that oven drying is the best of the 3 drying methods used for mistletoe obtained from almond host tree, thus confirming that diversity in drying methods leads to variation in phenolic constituents and biological activity of plants. |
URI: | 10.1177/2156587215600560 http://repository.elizadeuniversity.edu.ng/jspui/handle/20.500.12398/655 |
Appears in Collections: | Research Articles |
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Drying methods alter angiotensin_I converting enzyme inhibitory activity, antioxidant properties, and phenolic constituents of African Mistletoe _Loranthus bengwensis L_ Leaves.pdf | Article full-text | 375.75 kB | Adobe PDF | View/Open |
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