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|Title:||Drying methods alter angiotensin-I converting enzyme inhibitory activity, antioxidant properties, and phenolic constituents of African Mistletoe (Loranthus bengwensis L) Leaves|
Omojokun, Olasunkanmi S.
Ademiluyi, Adedayo O.
Angiotensin-I converting enzyme (ACE)
|Citation:||Oboh, G., Omojokun, O. S., & Ademiluyi, A. O. (2016). Drying methods alter angiotensin-I converting enzyme inhibitory activity, antioxidant properties, and phenolic constituents of African Mistletoe (Loranthus bengwensis L) Leaves. Journal of evidence-based complementary & alternative medicine, 21(4), 260-270.|
|Abstract:||This study investigated the most appropriate drying method (sun drying, oven drying, or air drying) for mistletoe leaves obtained from almond tree. The phenolic constituents were characterized using high-performance liquid chromatography–diode array detector, while the inhibitory effect of the aqueous extracts of the leaves on angiotensin-I converting enzyme (ACE) was determined in vitro as also the antioxidant properties. Oven-dried extract (kidney [276.09 μg/mL] and lungs [303.41 μg/mL]) had the highest inhibitory effect on ACE, while air-dried mistletoe extract (kidney [304.47 μg/mL] and lungs [438.72 μg/mL]) had the least. Furthermore, the extracts dose-dependently inhibited Fe2+ and sodium nitroprusside-induced lipid peroxidation in rat’s heart and kidney. Also, all extracts exhibited antioxidative properties as typified by their radical scavenging and Fe-chelating ability. Findings from this study revealed that oven drying is the best of the 3 drying methods used for mistletoe obtained from almond host tree, thus confirming that diversity in drying methods leads to variation in phenolic constituents and biological activity of plants.|
|Appears in Collections:||Research Articles|
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