Research Articles Biological Sciences

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Browsing Research Articles Biological Sciences by Author "Adebolu, T.T."

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    The effects of different treatments on the phytochemicals, proximate, and mineral contents of beniseeds (sesamum indicum linn)
    (Global Advanced Research Journal of Biotechnology, 2012-07-25) Momoh, A.O; Adebolu, T.T.; Ogundare, A.O.
    Sufficient Beniseeds were weighed and subjected to different treatments (fresh, roasted, boiled and fermented) to evaluate the effects of these treatments on the phytochemicals, proximate and mineral contents of the seeds. The qualitative phytochemical analysis shows the presence of tannin, phenol, saponin, alkaloid, phytate, oxalate, trypsin inhibitor and glycoside. Fermentation had significant effect on alkaloid, reducing its value from 11.13% in the fresh sample to 0.01% in the fermenting form by day three. Roasting had the highest significant effect on the saponin content of the seeds reducing it from 2.47% to 0.56%. Fermentation had the highest reducing effect on the anti-nutrients followed by roasting. The treatments had significant effect on the mineral content of the seeds. For instance, while boiling had reducing effect on the sodium, potassium and calcium content of the seeds, roasting had an increasing effect. Also, while boiling decreased the protein content from 21.28% in the fresh form to 17.41%, fermentation increased it to 29.93%.The results obtained in this work show that the subjection of beniseeds to different treatments has significant effect on its phytochemicals, minerals and nutrient contents of the seeds and these effects can be harnessed to make beniseeds a good nutraceutical supplement.
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    Therapeutic effect of beniseeds extract and fermented liquor in treatment of diarrhoea in albino rats infected with Bacillus cereus
    (2012-12-10) Momoh, A. O.; Adebolu, T.T.; Ogundare, A.O.
    The therapeutic efficacy of fermented beniseed liquor and the methanol extract in treating diarrhoea in albino rats infected with selected diarrhoeagenic bacteria was assessed. At the end of the experiment, haematological, biochemical and liver functioning tests were performed on the blood from the animals. The results showed that the selected organism have high infectivity dose, caused a significant reducing effect on the weight of the albino rats and negative effect on the hematological and biochemical parameters assessed. Treatment of infected animals with the fermented liquor and methanol extract of beniseeds showed that both caused a significantly quick recovery of the infected animals from diarrhoea within five days of treatment. However, the rate of recovery was faster with the group of infected rats treated with the fermented beniseed liquor than the extract. The results obtained from these analyses showed that beniseed have therapeutic properties and that the fermented form is more effective and can be used to treat diarrhoea caused by the selected bacteria used in this study in albino rats.