Drying methods alter angiotensin-I converting enzyme inhibitory activity, antioxidant properties, and phenolic constituents of African Mistletoe (Loranthus bengwensis L) Leaves

dc.contributor.authorOboh, Ganiyu
dc.contributor.authorOmojokun, Olasunkanmi S.
dc.contributor.authorAdemiluyi, Adedayo O.
dc.date.accessioned2020-01-30T16:12:18Z
dc.date.available2020-01-30T16:12:18Z
dc.date.issued2016-10
dc.description.abstractThis study investigated the most appropriate drying method (sun drying, oven drying, or air drying) for mistletoe leaves obtained from almond tree. The phenolic constituents were characterized using high-performance liquid chromatography–diode array detector, while the inhibitory effect of the aqueous extracts of the leaves on angiotensin-I converting enzyme (ACE) was determined in vitro as also the antioxidant properties. Oven-dried extract (kidney [276.09 μg/mL] and lungs [303.41 μg/mL]) had the highest inhibitory effect on ACE, while air-dried mistletoe extract (kidney [304.47 μg/mL] and lungs [438.72 μg/mL]) had the least. Furthermore, the extracts dose-dependently inhibited Fe2+ and sodium nitroprusside-induced lipid peroxidation in rat’s heart and kidney. Also, all extracts exhibited antioxidative properties as typified by their radical scavenging and Fe-chelating ability. Findings from this study revealed that oven drying is the best of the 3 drying methods used for mistletoe obtained from almond host tree, thus confirming that diversity in drying methods leads to variation in phenolic constituents and biological activity of plants.en_US
dc.identifier.citationOboh, G., Omojokun, O. S., & Ademiluyi, A. O. (2016). Drying methods alter angiotensin-I converting enzyme inhibitory activity, antioxidant properties, and phenolic constituents of African Mistletoe (Loranthus bengwensis L) Leaves. Journal of evidence-based complementary & alternative medicine, 21(4), 260-270.en_US
dc.identifier.uri10.1177/2156587215600560
dc.identifier.urihttp://repository.elizadeuniversity.edu.ng/handle/20.500.12398/655
dc.language.isoenen_US
dc.publisherSAGE Publicationsen_US
dc.subjectMistletoeen_US
dc.subjectAlmonden_US
dc.subjectDryingen_US
dc.subjectAntioxidanten_US
dc.subjectAngiotensin-I converting enzyme (ACE)en_US
dc.titleDrying methods alter angiotensin-I converting enzyme inhibitory activity, antioxidant properties, and phenolic constituents of African Mistletoe (Loranthus bengwensis L) Leavesen_US
dc.typeArticleen_US
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