Browsing by Author "Olofintoye, L. K."
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Item In vitro anthelmintic activity of three medicinal plants(IJRDO, 2016-07) Ojo, Adeola A.; Osho, I. B.; Adewole, S. O.; Olofintoye, L. K.In vitro anthelmintic assay of three medicinal plants was conducted to investigate which plants were anthelmintic. In vitro anthelmintic activity of all the three medicinal plants were carried out using earthworm at 50, 100, 200mg/ml of plant extracts from Vernonia amygdalina, Ocimum grattisimum and Talinum triangulare. Results showed that 200mg/ml was effective concentration for all the medicinal plants. Vernonia amygdalina showed faster anthelmintic than Ocimum grattisimum and Talinum triangulare. The plants can be used /employed in pharmaceutical industry to be used as anthelmintic drugs for treating livestocks affected with helminths.Item In vivo effects of four medicinal plants on nematodes of goat(2015) Ojo, Adeola A.; Osho, I. B.; Adewole, S. O.; Olofintoye, L. K.Medicinal plants are very cheap and accessible to rural people for treating ruminant’s diseases. The aim of this study was to investigate in vivo effects of four medicinal plants (Vernonia amgydalina, Ocimum grattisimum, Nicotiana tabacum and Talinum triangulare) on nematodes of goat. The ethanolic extracts of these medicinal plants were made and the dose used for the goats include 1 and 2 g/kg for Vernonia amgydalina, 1 and 2g/kg for Ocimum grattisimum, 0.5 and 1 g/kg for Nicotiana tabacum and 0.5 and 1 g/kg for Talinum triangulare. The goats were infected with L3 stage larval of nematodes of Trichostrongyle sp, Haemonchus contortus, Bunostomum and Strongloides sp and after the build up of worm after some days, they were treated using in vivo assay through oral administration of the plants extracts. The faecal samples were collected 3, 7 and 11 days and examined quantitatively through McMaster Counting technique for the number of parasites. The results showed that only 2g/kg of Vernonia amgydalina and 1g/kg of Talinum triangulare showed decreased of 91.6% and and 69% in the mean egg per gram (epg) output of the faecal sample. But other medicinal plants did not show any decrease in epg. This indicates that Vernonia amgydalina and Talinum triangulare could be used as antihelmintic plants to treat goat diseases thus helping to improve the health status of the goat.