Haematological and histopathological effects of oil from castor seeds (Ricinus communis Linn.) on albino-rats

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dc.contributor.authorMomoh, Abdul O.
dc.contributor.authorOladunmoye, M. K.
dc.contributor.authorAdebolu, T. T.
dc.date.accessioned2019-07-15T13:17:08Z
dc.date.available2019-07-15T13:17:08Z
dc.date.issued2012-07
dc.description.abstractThe effects of soxhlet extraction of oil from castor seeds (Ricinus communis Linn) using n-hexane as solvent on hematological and histopathological properties of albino rats was investigated using standard method. The haematological analysis of the animals’ blood showed that the extract caused a reduction in the packed cell volume (PCV) from 49.3 to 46.7%. Histopathological analysis of the organs of the animals showed that the extract caused dilation of the sinusoid with less prominent nucleus of the liver, homogeneity of the muscle fibres of the heart with inflammatory cell infiltration, infiltration of kidney cells with increased hyaline casts, while the small intestine showed acute erosion of superficial and middle parts of the intestinal villi. Since the oil has deleterious effects on the organs of the animals used and also reduced the PCV, it is conceivable that when the oil is consumed by humans, it will have the same effect. Therefore, it is advocated that the oil should not be consumed until further work is done on it.en_US
dc.identifier.citationMomoh, A. O., Oladunmoye, M. K., & Adebolu, T. T. (2012). Haematological and histopathological effects of oil from castor seeds (Ricinus communis Linn.) on albino-rats. Journal of Pharmacognosy and Phytotherapy, 4(4), 40-43.en_US
dc.identifier.issn2141-2502
dc.identifier.uri0.5897/JPP11.077
dc.identifier.urihttp://repository.elizadeuniversity.edu.ng/handle/20.500.12398/310
dc.language.isoenen_US
dc.publisherAcademic Journalsen_US
dc.subjectCastoren_US
dc.subjectOilen_US
dc.subjectAlbino ratsen_US
dc.subjectHaematologyen_US
dc.subjectHistopathologyen_US
dc.titleHaematological and histopathological effects of oil from castor seeds (Ricinus communis Linn.) on albino-ratsen_US
dc.typeArticleen_US
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