Effects of drying on cholinesterases and angiotensin‐I converting enzyme inhibitory potential and phenolic constituents of African mistletoe (Loranthus bengwensis L) leaves from kolanut host tree

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dc.contributor.authorOmojokun, Olasunkanmi S.
dc.contributor.authorOboh, Ganiyu
dc.contributor.authorAdemiluyi, Adedayo O.
dc.date.accessioned2020-01-30T16:12:36Z
dc.date.available2020-01-30T16:12:36Z
dc.date.issued2018-08
dc.description.abstractThis study investigated the most appropriate drying method (sun drying, oven drying, and shade drying) for mistletoe leaves obtained from kolanut tree. The phenolic constituents were characterized using high performance liquid chromatography–diode array detector, while the inhibitory effect of the aqueous extracts of the leaves on cholinesterases and angiotensin‐I converting enzyme (ACE) and antioxidant activities were determined in vitro. The extracts inhibited acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and ACE in dose‐dependent manner. However, extract from sun‐dried sample exhibited the highest AChE, BChE, and ACE inhibitory effect while extract from shade‐dried sample had the least. Likewise, sun‐dried sample exhibited the highest antioxidant properties as exemplified by Fe2+‐chelating, 1,1‐diphenyl‐2 picrylhdrazyl, OH, and nitric oxide radical scavenging abilities. This study also revealed the presence of 20 phenolic compounds with caffeic acid being the most predominant. Conclusively, kolanut host tree mistletoe leaves can be used as therapeutic agent in the management of Alzheimer's disease and hypertension.en_US
dc.identifier.citationOmojokun, O. S., Oboh, G., & Ademiluyi, A. O. (2018). Effects of drying on cholinesterases and angiotensin‐I converting enzyme inhibitory potential and phenolic constituents of African mistletoe (Loranthus bengwensis L) leaves from kolanut host tree. Journal of Food Biochemistry, 42(4), e12510.en_US
dc.identifier.urihttps://doi.org/10.1111/jfbc.12510
dc.identifier.urihttp://repository.elizadeuniversity.edu.ng/handle/20.500.12398/656
dc.language.isoenen_US
dc.publisherWiley Online Libraryen_US
dc.subjectAngiotensin‐I converting enzymeen_US
dc.subjectCholinesteraseen_US
dc.subjectDryingen_US
dc.subjectKolanuten_US
dc.subjectMistletoeen_US
dc.subjectPhenolicsen_US
dc.titleEffects of drying on cholinesterases and angiotensin‐I converting enzyme inhibitory potential and phenolic constituents of African mistletoe (Loranthus bengwensis L) leaves from kolanut host treeen_US
dc.typeArticleen_US
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