Arsenicosis in bladder pathology and schistosomiasis in Eggua, Nigeria
| dc.contributor.author | Bakare, Shukurat O. Bakarea | |
| dc.contributor.author | Adebayo, Adewale S. | |
| dc.contributor.author | Awobode, Henrietta O. | |
| dc.contributor.author | Onile, O.S. | |
| dc.contributor.author | Agunloyeb, Atinuke M. | |
| dc.contributor.author | Isokpehic, Raphael D. | |
| dc.contributor.author | Anumudu, Chiaka I. | |
| dc.date.accessioned | 2021-05-27T15:17:09Z | |
| dc.date.available | 2021-05-27T15:17:09Z | |
| dc.date.issued | 2018-06-02 | |
| dc.description | Staff Publication | en_US |
| dc.description.abstract | Background: Chronic schistosomiasis and arsenic exposure through drinking water are some of the risk factors for bladder cancer. To determine the association of schistosomiasis and arsenicosis with bladder pathologies, 122 individuals from Eggua in southwest Nigeria were recruited for this study. Methods: Prevalence of schistosomiasis was determined by urine microscopy and PCR. Total urinary arsenic concentration and arsenic levels in three different water sources in the community were assessed by flame atomic absorption spectrometry. Bladder pathologies were investigated by ultrasonography. The data collected were evaluated with chi-square (χ2) and ANOVA tests to examine the relationships among demographic factors, infection, bladder pathologies and urinary arsenic concentrations. Results: The prevalence and mean intensity of schistosomiasis were 21.3% and 20.7 eggs/10 mL urine, respectively. Arsenic concentration in two of the water sources, River Yewa (0.46 mg/L) and borehole (0.52 mg/L), were above the WHO standard (0.01 mg/L); and the mean concentration in urine samples, 1.17 mg/L, was also above the WHO standard (0.2 mg/L). There was no evidence of an association between bladder pathology and arsenicosis, or between schistosomiasis associated-bladder pathology and arsenicosis (p=0.66). Conclusions: Arsenicosis is a public health concern in the study population. At the moment no clear roles are envisaged for it in the development of bladder pathologies or urinary schistosomiasis-associated bladder pathologies in Eggua. | en_US |
| dc.identifier.uri | doi:10.1093/trstmh/try047 | |
| dc.identifier.uri | http://repository.elizadeuniversity.edu.ng/handle/20.500.12398/1030 | |
| dc.language.iso | en | en_US |
| dc.publisher | Trans R Soc Trop Med Hyg | en_US |
| dc.subject | arsenic contamination, | en_US |
| dc.subject | bladder tumour, | en_US |
| dc.subject | potable water, | en_US |
| dc.subject | rivers, | en_US |
| dc.subject | urogenital schistosomiasis | en_US |
| dc.title | Arsenicosis in bladder pathology and schistosomiasis in Eggua, Nigeria | en_US |
| dc.type | Article | en_US |