Mathematical Analysis of Sensitive Parameters on the Dynamical Spread of HIV

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dc.contributor.authorAdewale, S. O.
dc.contributor.authorOlopade, I. A.
dc.contributor.authorAjao, S. O.
dc.contributor.authorMohammed, I. T.
dc.date.accessioned2021-04-08T11:54:51Z
dc.date.available2021-04-08T11:54:51Z
dc.date.issued2016-05
dc.descriptionStaff Publicationen_US
dc.description.abstractSensitivity analysis was performed on a mathematical model of Human Immunodefiency Virus (HIV) to determine the gauge and importance of each parameter to basic reproduction number in the dynamical spread of the disease. The threshold basic reproduction number , 0 R which is the average number of secondary infection generated by infected individuals in his or her infectious period was calculated using next generation matrix method, which shows that, the disease dies out when R0  1, and the disease will persist and spread when 1 0 R  .The relative sensitivity analysis was computed for all the parameters in the basic reproduction number, which shows the influence of each parameter in the dynamical spread of the disease. Numerical sensitivity reveals that effective contact rate and progressor rate are the most sensitive parameters in the basic reproduction number. This analysis will help the medical practitioners and policy health makers to know the best control intervention strategies to be adopted in order to reduce dynamical spread of Human Immunodefiency Virus (HIV) in the communityen_US
dc.identifier.issn2319-8753
dc.identifier.urihttp://repository.elizadeuniversity.edu.ng/handle/20.500.12398/951
dc.language.isoenen_US
dc.publisherInternational Journal of Innovative Research in Science, Engineering and Technologyen_US
dc.subjectHIV,en_US
dc.subjectCritical Points,en_US
dc.subjectBasic Reproduction Number,en_US
dc.subjectLocal Stability,en_US
dc.subjectSensitivity;en_US
dc.titleMathematical Analysis of Sensitive Parameters on the Dynamical Spread of HIVen_US
dc.typeArticleen_US
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