Pesticides-induced Cardiovascular Dysfunctions: Prevalence and Associated Mechanisms

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dc.contributor.authorAdeyemi, Joseph A.
dc.contributor.authorUkwenya, Victor O.
dc.contributor.authorArowolo, O.K.
dc.contributor.authorOlise, Christian C.
dc.date.accessioned2021-06-21T12:27:15Z
dc.date.available2021-06-21T12:27:15Z
dc.date.issued2021
dc.descriptionStaff Publicationen_US
dc.description.abstractIncreased applications of pesticides, mainly in agriculture and public health, have resulted in increased chances of human exposure to pesticides. Chronic exposure to pesticides has been implicated in several human diseases, including cardiovascular diseases. Cardiovascular diseases are broadly used for various heart pathological conditions, including a defect in blood vessels, and they include myocardial infarction, atherosclerosis, stroke, cardiomyopathy, coronary heart disease, etc. In this review, the association between human exposure to pesticides and the development of cardiovascular diseases was discussed using epidemiological and laboratory data. The toxicokinetics of pesticides in humans was reviewed, as well as the risk factors for cardiovascular diseases. The important role of oxidative stress principally the induction of reactive oxygen species as the signaling molecules for various signaling pathways involved in pesticides-induced cardiovascular disease, was discussed.en_US
dc.identifier.citationJoseph A. Adeyemi*, Victor O. Ukwenya, Olatunbosun K. Arowolo and Christian C. Olise, “Pesticides-induced Cardiovascular Dysfunctions: Prevalence and Associated Mechanisms”, Current Hypertension Reviews 2021; 17(1) . https://doi.org/10.2174/1573402117666210111102508en_US
dc.identifier.issn1875-6506
dc.identifier.urihttps://doi.org/10.2174/1573402117666210111102508
dc.identifier.urihttp://repository.elizadeuniversity.edu.ng/handle/20.500.12398/1152
dc.language.isoenen_US
dc.publisherBentham Science Publisher : Current Hypertension Reviewsen_US
dc.subjectPesticides,en_US
dc.subjectoccupational exposure,en_US
dc.subjectcardiovascular diseases,en_US
dc.subjectoxidative stress,en_US
dc.subjectROS,en_US
dc.subjectendothelial dysfunction.en_US
dc.titlePesticides-induced Cardiovascular Dysfunctions: Prevalence and Associated Mechanismsen_US
dc.typeArticleen_US
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